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An adult patient with severe cerebral palsy developed several pressure ulcers after hospital admission for pneumonia. This one has persisted for many months. While it’s possible that the trauma that initiated it was a pressure injury, this is pyoderma gangrenosum. Note the ruffled, hypertrophic border, the purple margin and the new breakdown with hypertrophic vascular tissue along the edge. This was a very difficult case to treat and never fully resolved – although it did improve with oral steroids, intralesional Kenalog, oral cyclosporin and a variety of other interventions.

My goal with this case is not to discuss the treatment of PG (which is always challenging), but to show some of its many faces.

This is the best we managed to get it under control.

Although this is a blurry photo, this is how the PG looks as it activates again – easily mistaken for pressure but that’s the characteristic purple margin.


Dr. Fife sees patients at the CHI St. Luke's Hospital Wound Clinic in The Woodlands, Texas. For an appointment call (936) 266-2150.



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